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After scientists published a major study linking smoking to lung cancer in the 1950s, Philip Morris repositioned Marlboro as a men's cigarette in order to fit a market niche of men who were concerned about lung cancer while also concerned with masculinity if they smoked a filtered cigarette usually marketed to women

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Anticholinergics , such as tiotropium, offer longer benefits

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Jamie Hartmann-Boyce of the Centre for Evidence-Based Medicine at Oxford University, an author of a highly regarded review on HTP science published earlier this year, said the "important" paper "made some very good points"

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